Not to jump on anyone, but my personal experience may differ from others.
Back when I first became active again after some years of QRT, I got an old 2 meter rig and put it in the car. During a QSO with someone, I ran a red light in Vallejo and damn near got wiped out. Thanks to the other drivers who were watching out!. If it wasn't for the horrified look on my wife's face coupled with screeching tires, honks, I wouldn't have known I even did that.
Distracted driving is distracted driving no matter what the cause: Screaming kids in the back seat, texting, cell phones, even ham radio. I'll never operate from the car again unless the car is stopped .. or someone else is driving. The consequences, and I don't mean a ticket, are just not worth it.
73, Alan AD6E